The Effect Of Aggressive Immune Response Representing by Interleukin 6 (IL-6) In Patients With COVID19

Abstract

The pathogen that causes coronavirus disease in 2019 is the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) (COVID-19). COVID-19 has claimed the lives of 347,192 people worldwide as of May 25, 2020. According to the latest research, extremely unwell patients have a higher concentration of pro-inflammatory cytokines such as interleukin (IL)-6 than those who are moderately ill. In COVID-19, the high amount of cytokines also suggests a poor prognosis. Increasing evidence suggests that the "cytokine storm" may play a role in COVID-19 mortality. The clinical and pathologic aspects of the cytokine storm in COVID-19 are summarized here. SARS-Cov-2 specifically produces a high level of IL-6 and causes lymphocyte exhaustion, according to our findings. This study aims to show the effect of high immune response In patients of COVID19 that lead to what is called cytokine storm this storm must be prevented by inhibiting IL-6 to be more controlled cases.