Hemolytic Uremic Syndrom In Children

Abstract

Background: Hemolytic – uremic syndrome may be sporadic, epidemic, and in some countries e.g Argentina endemic. The disease occurs between the ages of 4 months and 4 years. The incidence of disease is increasing. Most but not all studies have shown that white children more susceptible to HUS than black children. Classic (post diarrheal) the disease occurs frequently during warmer months.

Objective: To assess the epidemiology, clinical presentation, laboratory studies, and important risk factor that affect the outcome.

Patients and method: A prospective cross-sectional study included thirty-six consecutive patients with Hemolytic – uremic syndrome in this study who fulfil the criteria of the diagnosis of HUS (microangiopathic hemolytic anemia, acute renal failure and Thrombocytopenia.Patients who need dialysis referred to the renal unit AL- Yarmouk Teaching Hospital for peritoneal dialysis.

Results: prodromal diarrheal was present in 32 cases (89%), 26 patients (72%) had dialysis; 10 patients required peritoneal dialysis once. significant association between; the younger age group (<2Years); non diarrheal prodrome; number of dialysis increasing risk of death in H.U.S cases.

Conclusion: there is an association between Hemolytic – uremic syndrome with substantial morbidity and the incidence of the syndrome is increasing particularly in young age child.