Potential Of Syringodium Isoetifolium On Hela Cell Lines

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Devi S , S. Shyamalagowri , J. Manjunathan , Sowmiya hari and Vidya karthikeyen

Abstract

Seagrass is a plant that lives in tidal areas, possesses unique secondary metabolites, which have roles as anticancer bioactive compounds. The aim of the present investigation was to evaluate the effect of in vitro anticancer and cytotoxic activity of the methanol extracts of Syringodium isoetifolium leaves, against the human HeLa cervical cancer cell line and to compare to the normal African green monkey kidney epithelial cell line (Vero) using the MTT colorimetric assay. Results showed that the methanol extract exhibits their potential as an anticancer agent. HeLa cell lethality by semi polar extract, polar extract and doxorubicin are 48.11%, 15.32 % and 48.75%, respectively. Ethyl acetic crude extract of fresh seagrass contain phytochemical compounds of alkaloid, terpenoid, polyphenol and flavonoid. The results suggest that the methanol extracts of S.isoetifolium exhibit greater activity on the HeLa cell line, meaning that these plant can be evaluated for potential promising anticancer activity.

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