The Relationship of Changes in the State of Connective Tissue and Hypomagnesemia in Juvenile Dysmenorrhea

Abstract

According to WHO, the prevalence of menstrual pain syndrome in the structure of adolescent gynecological pathology is extremely high, while about 15% of them characterize menstrual pain as excruciating [5]. Juvenile dysmenorrhea –JD) - painful menstruation in girls under 18 years of age in the absence of pelvic pathology is a common and often debilitating gynecological suffering regardless of age or nationality [2,4]. Despite the high prevalence, primary dysmenorrhea in girls is often poorly diagnosed and even ignored by medical professionals and by the girls themselves and their mothers, who may accept painful menstruation as a normal part of the menstrual cycle[1,3]. In the publications of a number of researchers, dysmenorrhea is listed among many manifestations of connective tissue dysmorphic disorder [6]. The main component of connective tissue is collagen fibers, and oxyproline is a biochemical marker of its decay [13]. Magnesium occupies a special place among the leading macro- and microelements involved in collagen biosynthesis.