Evaluation Of Antiulcer Activity Of Sangu Parpam- An Experimental Study

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Madhavan R, Murugesan R, Govindarajan Sumathy, Sathish Adithya R

Abstract

The Siddha System of Medicine is a traditional South Indian system of medicine. In the Siddha literature, Siddhar classified the diseases into 4448 and also mentioned the treatment for the diseases. Among the diseases that are classified, Gunmam is one of the diseases that is compared with Peptic Ulcer disease. As per the Siddha literature, Sangu Parpam is a unique medicine to treat the disease. Thus, the Sangu Parpam was prepared as per the literature and anti-ulcer activity was carried out by the methods of Pyloric ligation induced ulcer in rats and Ethanol/HCL induced ulcer in rats. The treatment with Sangu parpam shows a reduction in the gastric lesion area and promotes significant regeneration of the gastric mucosa in both methods. Thus, the traditional claim that Sangu Parpam is effective against peptic ulcers was proved. Further evaluation of the medicine is needed for its acceptance worldwide.Keywords: Peptic Ulcer Disease, Gunmam, Siddha, Sangu Parpam, Anti Ulcer Activity.

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