A study of ethanolic extract of Embeliaribes that may help prevent obesity in Wistar rats which have been in high-fat diet

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Zhanpeng Qi, Tan Wen Wu, Yolanda Dwiutami Gondowidjojo


Obesity and longer life "expectancy are major contributors to the rise in diabetes mellitus incidence over the last several decades (Heydari et al., 2010). There are now 366 million diabetics in the globe, with a projected increase to 552 million cases by 2030, according to current estimates (IDF, 2011). When it comes to diabetic patients per capita, India is the world leader, and it has earned the unenviable moniker "the diabetes capital of the world" (Mohan et al., 2007). According to the IDF's Diabetes Atlas (2012), India's current diabetes population of 63 million is predicted to grow to 101 million by 2030 unless immediate preventative measures are adopted. (IDF) (IDF, 2012). According to the International Diabetes Federation (IDF) and the Madras Diabetes Research Foundation, India had 62.4 million persons with type 2 diabetes in 2011, up from 50.8 million the year before (Shetty, 2012). Sims and colleagues notably created the word 'diabesity' in the 1970s to emphasise the tight connection between type 2 diabetes and obesity at that time (Haslam, 2010). The global epidemic of type 2 diabetes is being driven by rising obesity rates caused by insufficient physical exercise and high-energy diets (Zimmet et al., 2001). It is predicted that in the twenty-first century, obesity would be the leading cause of illness and mortality throughout the world. About 200 million men and almost 300 million women in the global adult population were classified as overweight or obese by the World Health Organization" (WHO) in 2012.

According to Dr. Anoop Misra and his team's "INDO-US joint research among Asian Indians, obesity was found to be 65.41 percent in urban regions and 31.8 percent in rural areas (NDOC, 2013). Indians are known to have distinct characteristics of obesity, including high levels of body fat, abdominal adiposity, increased subcutaneous and intra-abdominal fat, and the accumulation of adipose tissue in non-abdominal areas. Additionally, as" India's economic condition improves, the frequency of obesity among adults is on the rise.

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