Antifertility effect of Dactylorhiza hatagirea (D. Don) Soo. root extract using Cyclophosphamide induced male albino rats

Abstract

Dactylorhiza hatagirea is a curative orchid variety, which is used manage a sum total of disorganization with disease. The constituents have aphrodisiac nature along with further good being neuro stimulant, antibacterial, immunomodulator, than numerous healthful effects. The current research was carried out to look over the histopathological outcome of D. hatagirea on reproductive toxicity effect by CycloPhosphamide (CP) in male albino rats. In sub-chronic toxicity studies, the ethanolic extract of D. hatagirea were prepared and present exploratory animals exist cleave among six categories (G1 to G6).  Present study, G1 was examined as control; G2 and G3 was specified CP by varying doses and G4 and G5 were given ethanolic extract and G6 was administered with ethanolic extract and CP. At the end of experiments, the testes were detach and stained for histological examinations. The results of the study revealed prominent histopathological alterations with the degeneration of numerous disperse seminiferous tubules and appearance of uneven basement membrane