Metabolic Characteristics Of The Heart In Children With Chronic Kidney Disease.

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Murodova Malika Djamolovna , Yuldashev Botir Axmatovich , Mukhammedova Fariza Farkhodovna

Abstract

The most common causes of chronic kidney disease (CKD) in North America and Europe are diabetic nephropathy, hypertension, and glomerulonephritis. These three causes account for approximately 75% of all adult cases.


In pediatrics, the term "chronic kidney disease" was first used by R.J. Hogg in 2003 is identical to the term used in therapeutic practice. Currently, the definition and classification of CKD by stages in children do not differ from those in adults and is widely used in children's clinics and in scientific research. CKD aimed to determine the relationship between the degree of renal dysfunction and the various complications that arise, primarily from the cardiovascular system, as well as the risk of progression of CKD. In the early stages, it is important to determine the metabolic parameters of the heart; in cardiomyocytes, glucose breaks down – glycolysis. Therefore, an integrated approach is important in order to track the moment of the onset of changes in the cardiovascular system in the early stages to prevent the course of the disease and prevent complications.

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