Isolation, Characterization and Phytochemical Evaluation of Active Compound Thymol from Cyclea Peltata (Lam)

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Sonja Jose , B. Jaykar

Abstract

Cycleapeltata(Lam) belonging to the family Menispermaceae is a common plant seen in South India. It is mentioned in Ayurvedic classics by the name Rajapathaand is one of the important drugs used in Ayurveda therapeutics and is used widely in different formulations in medical practice. The quality control of herbal crude drugs and their bio constituents is of paramount importance in justifying their acceptability. The crude drugs can be identified systematically on the basis of their morphological, histological, chemical, physical and biological studies. Phytochemical screening reported the presence of alkaloids, carbohydrates, glycosides, phyto sterols compounds and proteins and amino acids. The plant widely used in the treatment of cough, fever, kidney disorder, urinary disorder and snake poisoning.Aim of the present study is to extraction and isolation of bioactive compound (Thymol) from Cycleapeltata(Lam) Hook. f. Thoms. The isolation and characterization analysis included Thin Layer Chromatography, High Performance Thin Layer Chromatography, GC-MS and Spectroscopy studies (IR, NMR, and MASS).The presences of thymol in the ethanolic fraction revealed that the isolated constituent is most active compound. Isolation of bioactive compound thymol may help in identification of various pharmacological activities and carrying out further research in C.peltata.

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