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Endometriosis is the spread of endometrial-like tissue into the uterus's target layer (adenomyosis) or beyond (external endometriosis). According to medical statistics, female endometriosis was considered the most common ailment in reproductive age, ranging from 12% to 50%.
In the structure of gynecological diseases, it ranked third after inflammatory processes and uterine fibroids. Itwas a common cause of reproductive disorders, up to the development of infertility, chronic pelvic pain syndrome, various mono and multiple organ pathologies (Strizhakov A.M., Davydov A.I., 1996; Adamyan L.V., Kulakov V.I., Andreeva E.N., 2006; Show R.W., 1995; Trealoar S.A. et al., 2005). Despite numerous theories, endometriosis, which explained the etiopathogenesis and the essence of the pathological process, but not one of them could explain the diversity of forms and manifestations of this disease, and clinical and morphological varieties were giving little results. The statistics confirmed the prevalence of endometriosis worldwide. This disease affected more than 170 million women of reproductive age, on average every 8-10 women. In Russia, in the structure of gynecological diseases, endometriosis occupied a leading place among the most common diseases of the pelvic organs, infectious-inflammatory and uterine fibroids. The frequency of detection of endometriosis during diagnostic laparoscopy for infertility was on average 25-50%. External genital endometriosis was diagnosed in 35% of patients applying to centres of assisted reproductive technologies for in vitro fertilization (IVF) (Adamyan L. V. Burgova E. N., Mikoyan V. D. et al. 2006 .; Adamyan L.V., Kulakov V.I., Andreeva E.N., 2006; Show R.W., 1995; Trealoar S.A. et al., 2005). The American Society for Reproductive Medicine had issued recommendations on this issue 2 times, which once again confirmed this topic's relevance. A revolutionary method of treating this disease was surgical, although hormonal therapy had not lost its importance as an independent treatment, and as adjuvant therapy in the preoperative period (Makhmudova GM, 2004 .; Adamyan L. V. Burgova E. N., Mikoyan V. D. et al. 2006 .; Adamyan L.V., Kulakov V.I., Andreeva E.N., 2006; Show R.W., 1995).