Antimicrobial Activity Of Clove Against Escherichia Coli And Candida Albicans İsolated From Urinary İnfections İn Women

Abstract

Urinary tract infections (UTIs) are one of the most frequent antimicrobial infections in women and men of all ages over the world. Syzygium aromaticum has been used in traditional medicine to treat microbial infections of the skin, mouth, urinary and vaginal tract. To evaluate Syzygium aromaticum for their antimicrobial activity against Escherichia coli and Candida albicans isolated from urinary tract infections. For this purpose,116 urine samples from women who were the subject of a complaint of urinary tract infection with ages ranging between (1-86) years. The recognition of microbial isolates was based on their physiological and morphological characteristics. Furthermore, The antimicrobial activity of Syzygium aromaticum against Escherichia coli and Candida albicans was investigated using the agar dilution method, were utilized in order to assess the minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC) and the minimum fungicidal concentration (MFC). In addition, disk diffusion and agar well diffusion method for determination of the zone of inhibition. Data were analyzed using a t-test with one-way analysis of variance (ANOVA), and the results were shown as the mean ± standard deviation (SD) by SPSS software and value of p<0.05 was considered statistically significant The results of this study indicated that C. albicans is less resistant to the cloves than the E. coli. Also, we observed that powder S. aromaticum have remarkable potential as an antimicrobial agent, deserving further investigation for clinical applications..