Metal Complexes Of The Schiff Base Of 1H-Indole-3-Carbaldehyde Were Produced And Their Catecholase Activities Were Assessed

Abstract

ThisTheSchiff base 4-(((E)-(1H-indol-3-yl)methylene)amino)-6-(((E)-indolin-3-ylmethylene)amino)benzene-1,3-dithiol was synthesized and characterized in this paper, which included 1H NMR spectroscopy. In the Schiff base reaction that led to the formation of the ligand, both ends of azmothine were involved. Four metal complexes [Cu(II) and Fe(III)] with chloride and thiocyanate groups (SCN–) in N- and N-indole ,N-azmothine and S-bonding modes were studied for their ability to mimic catecholase oxidase. All of the metal complexes are catalytically active, with complex3 having the highest turnover rate (kcat). The formation of H2O2 was revealed by the catalytic process as monitored by 1H NMR spectroscopy (isolation of 3, 5-DTBQ) and iodometric titration, implying that the mechanism of oxidation is through the formation of a semiquinolate species.