Natural Vs Therapeutic: An Insight On Wound Healing

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Habibullah , Muhammad Jamil , Amar Nasir , Muhammad Kashif , Atta Ur Rehman , Fateh Ullah , Abdul Rahman , Bibi Sadia , Imtiaz Khan , Imran Qazi , Muhammad Rasheed , Mubarik Ali

Abstract

Wounds on the skin can heal on their own through a process known as cutaneous wound healing. Haemostasis, inflammation, proliferation, and remodelling are the four stages of wound healing that are usually recognised. To close the wound and restore homeostasis in humans and animals, keratinocytes create a functional epidermis (reepithelialisation) as quickly as feasible. "Granulation tissue" is formed when dermal fibroblasts move into the wound bed and multiply, allowing for the formation of new blood vessels. In the end, the wounded tissue is returned to its pre-injury form over an extended period. Various skin diseases, such as nonhealing or chronic ulceration, can result from wound healing cascade dysfunction. For more than half of all medicines used today, indigenous, and traditional treatments rely heavily on natural ingredients and their derivatives. A detailed literature review has been carried out recognising the importance of traditional medicine and the use of medicinal plants and plant-based products to treat cutaneous wounds. Curcuma longa, Aloe vera and Camellia sinesis are some of the most often utilised wound healing products throughout a wide range of countries and ethnicities. Traditional techniques still have a lot to teach us, as seen by their continuous use and popularity. Natural products and derivatives from natural products are full of unknown combinations, reagents, and adjunct chemicals that potentially have a position in today's therapeutic arsenal.

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