THE MAIN CAUSES OF ANEMIA IN IRON AND VITAMIN B 12 DEFICIENCY ASSOCIATED WITH HELICOBACTER PYLORI

Abstract

The article is generally devoted to anemia and iron deficiency associated with HELICOBACTER PYLORI. The causes of the disease, world statistics, types and treatment modules are also given. The most common consequence of H. pylori infection is iron deficiency. It occurs primarily due to chronic blood loss in erosive gastritis, ulcerative defects, cancer, defects in the gastric mucosa in MALT lymphoma. Another mechanism for the development of iron deficiency is similar to the mechanism for the development of anemia in chronic disease. The synthesis of hepcidin (a peptide that regulates iron absorption) is increased, as a result of which the absorption of iron and its increased deposition in macrophages are blocked at the level of enterocytes. The reason for the development of iron deficiency may be a decrease in the absorption of non-heme iron (iron from plant products) at the level of enterocytes - achlorhydria.