COORDINATION OF TREATMENT GUIDELINES FOR IRON DEFICIENCY AND B12 DEFICIENCY ANEMIA ASSOCIATED WITH HELICOBACTER PYLORI

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Lutfulla S. Makhmonov , Akmal U. Yigitov , Dilafruz A. Amerova , Nuriddin N. Temirov

Abstract

Iron deficiency is a common complication of Helicobacter pylori infection and can be asymptomatic or with symptoms of sideropenia, up to the development of anemia.


One of the mechanisms for the development of iron deficiency is chronic inflammation, as a result of which the expression of the iron-regulating protein hepcidin increases. Increased expression of hepcidin leads to the development of iron deficiency in patients infected with Helicobacter pylori.


Effective treatment of iron deficiency is possible only after the suppression of the inflammatory syndrome and a decrease in the increased level of gypsidine with successful eradication of H. pylori. This article presents scientific theoretical views on this topic.

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