Synthesis, Characterization Of 1, 3-Thiazine Derivatives Using Chalcones, And Evaluation As Antimicrobial

Abstract

This study is concerned with the synthesis and characterization of the 1, 3-thiazine derivatives. These compounds (d-f) were prepared by reacting of Thiosemicarbazide with the appropriate chalcones (d-f) in the presence of sodium hydroxide in ethanolrefluxed on water bath for 6 hrs, and the completion of the reaction was emphasize by thin layer chromatography (TLC), and the formed compounds were identified by NMR, IR,. The proposed reaction for their formations , And testing these organic compounds as antimicrobials