The Molecular Variation Of Wzxand Wzygenes In Multi Drugs Resistant Pseudomonasaeruginosa Isolated From Wounds

Abstract

Pseudomonas aeruginosa infection is one of the health problems in hospital patients, the multi-drug resistance isolates were enrolled in the present study to detect genetic variation of some B-band LPS synthesis genes, the wzxandwzy genes were detection using monoplex-PCR, the results shows that the wzx was detected in 87.5% of isolates while didn’t found in 12.2%, the wzy gene found in the 50% of isolates, the other variations were found both genes (wzx+wzy) in 50%, and 37.5% of isolates have wzx without wzy, and 12.5% have wzy without wzx, The present study concluded that the genetic variants of B-band (wzxandwzy) involvement in the wound infections and multidrug resistance of P. aeruginosa.