Evaluate Humoral And Cellular Immunological Parameters In Covid 19 Patients At Iraq

Abstract

This study was aimed to isolate and identify the viral load and positive virus infection in patients with COVID19, evaluate humoral and cellular immunological parameters against those viral infections, and studying the effect of some antibiotics on viral isolates in COVID19, patients admitted to COVID19 center in Al Hussain hospital from first Jan 2021 to end of Mars 2021. A total of 200 individuals were subjected to this study with the age range (28-55 years). SARS-CoV-2 patients with signs and symptoms of infections were 92 individuals and the rest (58) from SARS-CoV-2 patients apparently not infected symptoms and pathological signals. it also contains 50 normal individuals as a control group at the same age range. viral load was the main predominant that constitute 23:58 (39.65%) of another group were the main predominant third group isolate 7:17 (41.17%). followed by the rate of infected 5:17 (29.4%). The immunological parameters showing that there is a significantly increased (p<0.05) in the level of IgG in infected patients (17753) compared with control and significantly increased (p<0.05) non-infected (14653) and normal persons (10380) mg/L, IgM insignificantly increased (p>0.05) in the same patient groups and normal persons (1370,1296,1275) mg/L, C3 level is a significantly increased (p<0.05) in the same patients' group and normal persons (1620,1243,1220)mg/L, C4 level insignificantly increased (p>0.05) in the same patient group and normal persons (375,357,325 )mg/L, serum ferritin concentration is a significantly increased (p<0.05) in the same patient group and normal persons (350, 295, 87 ) ng/ml.