Effect Of Typha Domingensis Plant Antigen On Ige, Cd3, Cd300 Parameter Of Allergic Asthmatic And Bronchial Patients In Basra, Iraq

Abstract

Background & objectives:A study to determine the effect of plant antigen TYPHA on patients with allergic asthma and bronchitis by estimating the level of immunological parameters IgE, CD23, CD300.
Method: 75 samples were collected from patients with allergic asthma and bronchitis, and 15 samples were collected from healthy people from the Allergy and Asthma Center, their ages ranged between (20-<50). Serum was collected at a rate of 1 cm 3 in 1.5 cm 3 tubes.
Result:Results showed an increase in the number of people, the allergic to antigen of the papyrus plant, as their number reached 49 out of a total of 75 samples, at a rate of (65.3%) , The asthma patients was more sensitive to antigen Typha sp. plant, from patients allergic bronchitis by (49.3%), with a significant difference between them at the probability level (p < 0.05). Also results of the study showed that the percentage of females sensitive to the antigen of the Typha sp. plant was higher compared to males and it reached (38.7%), with a significant difference between them at the level of probability (p < 0.05As well as , the results of the study showed that first age group (29-20) highest age group sensitive to the antigen Typha sp. plant at rate (21.3%) compared with the other age groups with significant differences between other age groups . Asthe study showed an increase in the concentration of CD23 differential protein among those sensitive to the antigen of the Typha sp. plant at a concentration of 2400 (IU/cm3) and by 36% compared with the non-sensitive with a significant difference between them at the probability level (p < 0.05). The current study showed an increase in the differential protein CD300 concentration in those sensitive to the antigen of the Typha sp. plant at concentration 4 (IU/cm3) by 32% compared with the non-sensitive with a significant difference between them at the probability level (p < 0.05).
Conclusion: Exposure to Typha sp. plant antigen affects the immune system of asthmatics. So we think this is the reason for the increase in asthma.