Anti-Mullerian Hormone, Antral Follicle Count, Follicle Stimulating Hormone As An Indicators Of The Ovarium Response In Stimulation

Abstract

Background: Gynecology treatment needs a personal approach to each patient, especially in conduction the controlled ovarian stimulation protocol. And control of the special hormones range can be a help to choose the correct cure protocol.
The main aim of the research was to compare the value of AMH, AFC and FSH for indentifying ovarian-response in in-vitro fertilization.
Materials and Methods. The research was conducted at Haiphong hospital of obstetrics and gynecology from 1/2017 to 1/2018. A prospective study was conducted 507 patients. On cycle day 2, each person had anti-mullerian hormone, antral follicle count and follicle stimulating hormone measured.
Results: Anti-mullerian hormone test was the most accurate in predicting poor and hyper response, followed by antral follicle count and the least one was follicle stimulating hormone. Anti-mullerian hormone rate 1.31ng/mL predicted poor response with sensitivity of 74% and specificity of 86.9%. Anti-mullerian hormone rate 3.31ng/mL predicted hyper-response with sensitivity of 85.6% and specificity of 71.9%.
Conclusions: Anti-mullerian hormone test has the best predictive value for predicting ovarian response.