Prevalence Rate Of Metabolic Syndrome Among Patients With Acute Coronary Syndrome

Abstract

Background andAim:
Cardiovascular diseases are the main cause of death in both developed and developing countries, and coronary artery disease
(CAD) is the most frequent cause of cardiovascular mortality the metabolic syndrome, This study aims to evaluate the prevalence
rate of metabolic syndrome between patients with Acute Coronary Syndrome admitted in Coronary Care Unit and its impact on
severity of coronary lesions.
Patients and methods:
The study included (400) patients presented with acute coronary syndrome admitted in CCU in Sohag Specialized Cardiac and
Digestive System Center, The study included 287 males (71,8%) and 113 females (28,2%)
Patients with ACS were categorized according to the presence or absence of MetS at baseline, using the 2009 definition by
the National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis
Society; and International Association for the Study of Obesity.
The Patients were Classified in to Two Groups :
- Group (Mets): included 230 patients with metabolic syndrome.
- Group (Non-Mets): included 170 patients with non-metabolic syndrome.
Results :
As totally, the prevalence rate of metabolic syndrome between patients of ACS in our study was 230 patients(57.5%).230 patients
with metabolic syndrome,70%males&30% females andno statistically significant difference between mets and gender.Waist
circumference ranged from 70-123cm with a mean ± SD( 96.77± 10.35)of mets patients ,&there was high statistically significant
relationship between mets and waist circumference.(p_value<0,001)Weight ranged from 65-125kg , with a mean ± SD (88.10±
11.25) of mets patients &there was high statistically significant relationship between mets and weight (p_ value<0,001).178
hypertensive patients (77.39%), and 52 non-hypertensive(22.61%) of Mets patients& there was high statistically significant
relationship between mets patients and hypertension.There was high statistically significant decrease in the level of
HDL(36.06±10.86 vs44.21±14.49; P < 0.001), increase in the level of triglyceride (170.42±77.20 vs122.48±46.12; P < 0.001) and
cholesterol ( 192.15±56.40 vs174.08 ±56.81; P < 0.002) in metabolic patients than non metabolic patients . Coronary angigrophy
results of mets patients included 35 patients with normal CA (15.29%), 18 patients for medical treatment (7.82%),139 patients for
PCI (60.43%) ,38patients for CABG(16.52%).As totally 177 patients of mets patients had a significant lesion of coronary
vessels(76.95%)
Conclusion :
Prevalence of metabolic syndrome is high in patients with coronary artery disease .Patients with metabolic syndrome have more
severe coronary artery disease, so metabolic syndrome can be used as a tool for predicting severe CAD.