Chromosomal changes of chronic lymphocytic leukemia in Al Kut

Abstract

Background and Objectives: Analyze the chromosomes of patients with chronic lymphocytic leukemia (CLL) in Kut to identify chromosomal abnormalities and study the chromosomal changes in patients.
Patients and Methods: Clinical notes and cytogenetic analysis were studied for all patients. Cases were collected from oncology unit at Al Karama Hospital in Al Kut.
Results: Chromosomal analysis of all patients showed chromosomal aberrations, It was found that most of the chromosomal changes are structural changes. The abnormalities of the patients' chromosomes were divided according to their karyotype into 3 groups: chromosomal bridge (36.8 ) , complex chromosomes (31.6 ) and normal (31.6 ) .
Conclusion: Chromosomal abnormalities, especially structural abnormalities are responsible for the occurrence and development of chronic lymphocytic leukemia and the high complexity of karyotyping of patients.