Chromosomes Of Children With Acute Lymphocytic Leukemia In Al Kut

Abstract

Background and Objectives: analyze the chromosomes of children with acute lymphocytic leukemia (cALL) in Kut to identify chromosomal abnormalities and study the chromosomal changes in patients.
Patients and Methods: Clinical notes and cytogenetic analysis were studied for all patients. Cases were collected from oncology unit at Al Karama Hospital in Al Kut.
Results: Chromosomal analysis of all patients showed chromosomal aberrations, and most of the aberrations were numericalabnormalities, were divided according to their karyotype into 4 groups: hyperdiploidy(47%), hypodiploidy(29.4%), pseudodiploidy(5.9%), and normal karyotype(17.5%).
Conclusion: Chromosomal abnormalities, particularly numerical abnormalities, are associated with the development of acute leukemia and the high complexity of karyotyping of patients.