Single Flap Approach With And Without Platelet Rich Fibrin In The Management Of Intrabony Periodontal Defects – A Randomized Controlled Trial

Abstract

Aims
This Randomized controlled study was conducted to evaluate the effect of the Single Flap Approach with and without Platelet Rich Fibrin on clinical parameters of periodontal disease, when used to manage intra-bony periodontal defects.
Materials and Methods
Fortyintra-bony sites were studied. Twenty sites were surgically accessed with Single Flap Approach + Platelet Rich Fibrin and twenty sites were accessed with Single Flap Approach alone. The Single Flap Approach consisted of an oblique or horizontal butt joint incision is made at the level of the inter-dental papilla. Only the buccal flap was raised while the inter-dental papilla was left in situ. The granulation tissue filling the defect was dissected and removed, leaving the inter-dental and palatal/lingual tissues untouched in both the groups. Additionally,Platelet Rich Fibrin was placed into the defectin Single Flap Approach + Platelet Rich Fibrin group. Primary closure of the flaps was attained with vertical internal mattresssuture.
Results
Early wound healing was attained and maintained in all sites in Single Flap Approach + PlateletRich Fibrin group, while the Probing depth reduction was 3.7 ± 0.17 in Single Flap Approach + Platelet Rich Fibrin group and 3.75 ± 0.91 in Single Flap Approach alone group. The 6-monthClinical attachment level gain was 3.4± 0.87in Single Flap Approach +Platelet Rich Fibringroup and 2.7 ± 1.36 in Single Flap Approach alonegroup.
Conclusion
SFA+PRF resulted in better early wound healing and greater Clinical Attachment gain than SFA alone.