Evaluation Ofchemockin Ligand 2 (CCL2) And Interferon Gama Levels (INF-Γ) In The Serum Of Chronic Liver Disease Patients

Abstract

In the presentstudy, 70of patients were suffering from chronic liver diseaseand 20 of control group, were 35 females and
35 males of patients. The samples were collected from Gastroenterology and Hepatology Center in AL-Sadder Medical
City/Najaf Governorate / Iraq , the period from July till August, 2019. The ages of CLDpatients and healthy group ranged
30 to 69 y old. And the patients group was divided into subgroup accordingto the age and gender group , Patients without
a complete medical record were excluded and those with other diseases e.g. (Alcoholic liver damage , acute liver damage
and viral hepatitis were excluded.
The current study indicated a highly significant enhance(p<0.05)inserum CCL2/MCP-1 and INF-γlevels in CLD compared
with healthygroup. The result indicated no significant differences(p>0.05) in serum levels of CCL2/MCP-1 and INFγbetween females and males groups of CLD patients. The results, also indicated asignificant enhance(p>0.05)in serum
CCL2/MCP-1, and INF-γlevels there was asignificant increase (p<0.05)among different ages groups. There is a positive
association between CCL2/MCP-1 and INF-γconcentrations of CLD patients
Conclusion.:The present study conducted that CCL2/MCP-1 and INF-γlevels were good markers for diagnosisand detection
of chronic liver disease in both genders the males and females.