The Role Of Meconium-Stained Liquor In Histopathological And Immunohistochemical Changes In Term Maternal Placenta

Abstract

The current research focuses on certain histopathological of the placenta related with Meconium stained liquor (MSL) and immunohistochemical technical in the study groups. The samples were taken (maternal placental tissue) from 30 women with MSL and 30 control women with clear liquor in labour. The placenta samples were collected and preserved in formalin (10%) for histological study and ethanol (70%) for the immunohistochemical study were obtained from AL-Liqa Hospital for Maternity and Al - Yarmouk Teaching Hospital. Samples were collected from January to June 2021. The mean age of cases with MSL were 26.1±6.44 years compared with the mean age of clear liquor stain as control group 21.8±4.88 year. Histopathological changes in the placenta showed highly significant differences between the two study groups (Intervillous space, intravillous fibrinoid, perivillous fibrinoid, calcification, fibrosis, syncytial knots, blood vessel changes). Immunohistochemical All result is significant at p < 0.01.