“Design And Characterization Of Mosquito Repellent Emulgel Formulations For Circumventing Infectious Diseases”

Abstract

Background: Herbal based essential oil (EO) containing catnip & citronella has been reported as an excellent mosquito repellent. But mild sensitive and volatile nature limit its topical application and hence it was intended to formulate a non-irritant, safe, and consistent product emulgel with sustained abode time on skin.
Results: The emulgel was made using solvent dispersion technique. Sensory evaluation, accuracy pH, softness, greasiness, and stickiness were all measured. The optimised batch (F4) was showing the viscosity (90249.67±139.95 cP), profile of texture (70.33±0.88 mg) as well as extrudability (639.62± 8.09 mg). In contrast to the other mosquito repellents, F4 was found to have been secure for more than 90 days, as well as having a longer period in relation to repellency against mosquitoes.
Conclusions: Citronella and catnip oil in F4 were found to be intact using HS-GC. The primary annoyance index (PII 0.45) assigned F4 to the irritation barely perceptible category. Formulation F4 with distinct stability, texture profile, extended residence time on skin and lower the promise of PII have been observed. Industrial application and provided a promising substitute for synthetically produced products.