Synthesis, Characterization For New (Heterocyclic) Compounds From 2-Amino-6-Methoxy Benzothiazole And Study Biological Activity

Abstract

The aim of the present study is synthesis heterocyclic compound by many steps . The first step react 2-amino-6-methoxy benzothiazole with 2,4-dimethoxy acetophenone to get azo compound (1) . The second step involve react (1) with vaniline to get chalcone compound (2) . the last step is react (2) with hydrazine, phenyl hydrazine , 2,4-dinitro phenyl hydrazine to form pyrazol derivatives (3-5) and react compound (2) with malononitrile to form pyridine derivative (6) and react compound (2) with quandine hydrochloride to obtain the pyrimidine derivative (7) and react compound (2) with thiourea to obtain thiazine derivative(8) . All prepared compounds have been diagnosed by (FT-IR and 1H-NMR ) Spectroscopy and after diagnosis of spectra compound their biological effect was studied on two type anticancer and antioxidant .