A Review On Recent Approach In Synthetic Methods, Chemical Characteristics And Biological Potential Of Triazine And Quinazolinone Derivatives

Abstract

Triazine and Quinazolinone is an attractive class of heterocyclic compounds. Numerous synthetic
analogs of triazineand Quinazoninone have been prepared and evaluated for many pharmacological
activities in different models. Some analogs have shown potent pharmacological activity and may be
considered as lead molecule for the development of future drugs. Triazine and Quinazolonione ware
first synthesized over a century ago, but still attracts the attention of scientists, chemists, biologists,
and other specialists. In recent years, antiviral, anti-inflammatory, antifertility, anti-tubercular activity,
anticancer activity, antimicrobial activity, antimalarial activity, protein kinase inhibitor activity, antiangiogenic activity, anti-trypanosomal activity, the antioxidant activity of triazine have been published.
This review is an attempt to organize the chemical and pharmacological aspects of triazines and
Quinazolinoeanalogs reported to date systematically since 1970.