Prevalence Of Some Viruses Related To GIT Cancers Among Patients In South Area Of Iraq

Abstract

The study was investigated and diagnosis the viruses that associated with GIT cancer and GIT diseases a
total of 200 blood and biopsy samples were collected during the period from September 2020 to June 2021
and samples were included 100 sample for gastrointestinal cancer patients, 50 for healthy people, and 50
for gastrointestinal patients. Gastrointestinal tract diseases patients were diagnosed clinically and the
disease was evaluated by specialist physicians, presented with dyspepsia referred to the Esophago
Gastroduodeno Scope Unit for endoscopy at AL-Hussein teaching hospital (Consulting digestive tract), the
results revealed, three types of viruses were diagnosed that are related to diseases of the digestive system,
with regard to viruses, including: Human papilloma viruses (HPVs), The Epstein-Barr virus (EBV), Polyoma
virus (MCPV) and Human herpes virus (HHV) by PCR technique, however the percentage of existence of
these viruses was higher in patients with cancer than in patients with GIT disease as following : the present
of Hpv18 gene was (13%) in patients with cancer, while in patients with GIT diseases (13%) but in the healthy
(0 %) , while the results of EBV genes showed EBNA1 in patients with cancer (24%) but (14%) in GIT diseases
patients , in the healthy was (10%), whereas the percentage of Polyoma virus genes (VP1 and VP2 genes)
(28 %) in people with cancer, but in patients with GIT diseases (26%), healthy people (20%) with significant
differences between those groups .Our findings supported the hypothesis these viruses can be has a place
in etiology of gastrointestinal cancer.