Molecular Identification And Prevalence Rate Of Hepatitis C Virus Among Hemodialysis Patients In Peshawar Kp Pakistan

Abstract

Hepatitis C Virus remains a significant risk for both patients and medical staff in hemodialysis centres. The current
study aims to determine the infection rate of hepatitis C virus, and risk factors associated with hepatitis C virus in
hemodialysis patients admitted in Hayatabad Medical Complex Peshawar. A cross-sectional study was based on the
processing of blood samples from 306 hemodialysis patients with routine hemodialysis were collected during the
period16thSeptember 2020 till 16th December 2020 at Hayatabad Medical Complex Peshawar. After preparation of
samples, enzyme-linked immunosorbent assay test was performed to detect on hepatitis C virus –antibody
(Immunoglobulin G), then the seropositivity samples confirmed by real-time polymerase chain reaction technique.
The rate of hepatitis C virus infection among hemodialysis patients in Hayatabad Medical Complex Peshawar was
7.8% (24/306), and there were no differences between males and females (12 cases) for each case. Age between
61-70 years was the most likely 9(37.5%). There were no Environmental differences between the patients of Peshawar or around Peshawar (50%) for each one, and 22 married patients (91.70%) more than unmarried 2(8.30%).
Patients with primary education were more frequent 9 (37.50%),hemodialysis duration ranging from 1-4 years
showed more frequent than other periods 21 (87.5%). The rate of hepatitis C virus infection was moderate among
hemodialysis patients in Hayatabad Medical Complex Peshawar and there are no differences between gender and
residence and the infection increases with the duration of dialysis.