Evaluation of Biochemical effects of Famous Unani Herbal Product “Arq-e-Gulab” on Cardiac Enzymes

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Muhammad Osama
Rahila Ikram
Calvin R. Wei
Raheela Saleem
Ghulam Rasool Bhurgri
Fahad Jibran Siyal
Nadeem

Abstract

Prehistorically, the use of plants and plant-based products have often been considered for their medicinal properties in treating unhealthy states. The main reason of people preference of using plant based products is their low cost, accessibility, and minimal unwanted effects. There is widespread assumption that such products are safe to use. Furthermore, awareness and reporting culture of adverse events with plant-based products is very uncommon all over the world. Arq-e-Gulab (AG) is a famous Unani herbal preparation which is commonly known as Rose Water prepared by water-distillation of rose petals of Rosa damascena Mill. flower. It is traditionally used in various eye preparation to treat ophthalmic allergies and inflammatory condition. It is also used in cooking as flavoring agent in preparation of various sweets and meat recipes especially in Asian region. This study aims to investigate the impact of chronic dosing of AG on cardiac enzymes to evaluate its effect on heart. This study was carried out on albino rabbits. AG was given at two different doses for 60 days for evaluation of biochemical effects. Our study reveals that AG does not possess any cardio-toxic effects.


 


 

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Author Biographies

Muhammad Osama

Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan.

Rahila Ikram

Faculty of Pharmacy, Salim Habib University, Karachi, Pakistan.

Calvin R. Wei

Department of Research and Development, Shing Huei Group, Taipei, Taiwan.

Raheela Saleem

College of Pharmacy, Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan

Ghulam Rasool Bhurgri

Department of Pharmacology & Therapeutics, Indus Medical College, University of Modern Science, Tando Muhammad Khan, Sindh, Pakistan.

Fahad Jibran Siyal

Department of Pharmacology, Chandka Medical College, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh, Pakistan

Nadeem

Department of Pharmacology, Chandka Medical College, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh, Pakistan.