In-vitro Evaluation of Antioxidant and Antidiabetic Potential of Traditional Herb Rosa Centifolia L.

Abstract

Objective: The current work aimed to discover the antioxidant and antidiabetic potential of the Rosa centifolia L. fresh Petals extract, which belongs to the Family Rosaceae.

Material and Methods: The authenticated flowers of Rosa centifolia were subjected to the soxhlet extraction method. The phenolic content of ethanolic extract has attracted a great deal of attention. The crude ethanolic extract of Rosa centifolia L. flower was fractionated with different solvents, chromatographic separation was performed, and their TLC parameters were studied to know the presence of active phytochemicals. The Rosa centifolia L. petals antioxidant and antidiabetic potential have been studied as there were no previous research data available in the literature. The eluted fractions were screened for bioactivity through an in-vitro assay.

Results: The extract yielded various fractions through column chromatography. Sub-fraction F6.4.2 demonstrated a potent in-vivo antioxidant and antidiabetic potential compared to the other mother fraction and fraction. The bioactive effects of the sub-fractions F6.4.2 against antioxidant and antidiabetic in vitro show maximum.

Conclusion: The present research work would be beneficial to enhance the data availability concerning antioxidant and antidiabetic assessment to the investigation in the traditional system and in modern medicine for the medicinal use of herbal drugs